Hormonal Peptide
PT-141
Bremelanotide — Sexual health peptide
Starting at $295
PT-141 (Bremelanotide) is an FDA-approved melanocortin receptor agonist that activates central nervous system pathways regulating sexual arousal in both men and women. Unlike PDE5 inhibitors (Viagra, Cialis), PT-141 works through the brain — effective regardless of hormonal status or vascular health.
Central nervous system sexual activation.
PT-141 activates MC3R and MC4R receptors in the hypothalamus — directly stimulating sexual arousal through the brain's own reward and desire pathways.
Melanocortin Receptors
MC3R / MC4R Activation
Activates melanocortin 3 and 4 receptors in the hypothalamus — directly stimulating the dopaminergic pathways that mediate sexual desire and arousal. This central mechanism works regardless of hormonal status or vascular function.
Result: Direct CNS-mediated enhancement of sexual desire and arousal
Reward Pathway
Dopamine Release
MC4R activation triggers dopamine release in reward circuits, producing genuine increases in sexual motivation rather than just mechanical enhancement.
Result: Increased sexual motivation and desire in both men and women
Erectile & Arousal Function
Peripheral Effects
In men, MC4R activation also promotes penile erection through a pathway independent of PDE5. In women, vaginal engorgement and clitoral sensitivity increase. Works in patients unresponsive to PDE5 inhibitors.
Result: Effective for both men and women, including PDE5 non-responders
Clinical Benefits
What you can expect from PT-141 therapy
Increases sexual desire
FDA-approved for hypoactive sexual desire disorder (HSDD) in premenopausal women — the first medication of its kind.
Erectile dysfunction
Effective for men with ED, particularly those with psychological or central components, or PDE5 inhibitor non-responders.
Works for men and women
Unique CNS mechanism makes it effective for both sexes — one of the few sexual health medications validated in women.
Vascular independence
Works through the brain, not blood flow — effective even with vascular or hormonal factors that limit PDE5 inhibitors.
Rapid onset
Effects typically begin 30–60 minutes after administration, lasting several hours.
FDA clearance
Approved as Vyleesi (bremelanotide) by the FDA for HSDD, providing an established safety database.
The Process
What to expect & when
Realistic timeline for PT-141 results
30–60 minutes
Acute Sexual Arousal
Onset of central and peripheral sexual arousal effects, typically peaking within 1–2 hours.
2–8 hours
Duration of Effect
Effects last several hours — taken approximately 45 minutes before anticipated sexual activity.
Common questions
Everything you need to know about PT-141 therapy
Transparent Pricing
Consultation Fees
Physician-guided care with complete pricing clarity.
Generic Consultation
Includes Any & All Services
First Visit
$400
Follow-Up
$150
- Complete health assessment
- All service areas covered
- Personalized treatment plan
- Prescription if appropriate
Specialized Consultation
Skin, Hair, Wellness, Labs, Galleri
First Visit
$300
Follow-Up
$150
- Focused specialty review
- Lab analysis included
- Targeted treatment approach
- Follow-up protocol
Peptide Consultation
Weight loss & metabolic therapies
First Visit
$50
Follow-Up
$30
- Metabolic assessment
- GLP-1 or peptide evaluation
- Dosing strategy
- Prescription included