Anabolic Growth Factor

IGF-LR3
Insulin-like Growth Factor Long R3

Starting at $300

IGF-LR3 (Insulin-like Growth Factor-1 Long R3) is a modified form of IGF-1 with significantly extended half-life and potency. It directly stimulates muscle cell growth, fat oxidation, and tissue repair — acting downstream of GH to produce anabolic and regenerative effects with greater duration than native IGF-1.

Licensed Metabolic MDsDaily subcutaneous injectionResults in 2–6 weeks
IGF-LR3 peptide therapy

Direct anabolic signaling.

Unlike GH secretagogues that stimulate the pituitary, IGF-LR3 acts directly on IGF-1 receptors throughout the body — bypassing the GH-liver axis for immediate anabolic action.

1

Direct Anabolic

IGF-1 Receptor Activation

Binds directly to IGF-1 receptors on muscle cells, triggering protein synthesis, hyperplasia (new cell creation), and hypertrophy (cell size increase) — the fundamental mechanisms of muscle growth.

Result: Direct stimulation of muscle protein synthesis and growth

2

Long R3 Modification

Extended Half-Life

The 'Long R3' modification reduces binding to IGF binding proteins (IGFBPs), extending the active half-life from minutes (native IGF-1) to hours — producing sustained anabolic signaling throughout the day.

Result: Prolonged anabolic signaling from a single daily injection

3

Lipolysis

Fat Oxidation

IGF-LR3 activates adipocyte lipolysis — the breakdown of stored fat for fuel — while simultaneously building lean tissue, producing potent body recomposition effects.

Result: Simultaneous muscle gain and fat loss (body recomposition)

Clinical Benefits

What you can expect from IGF-LR3 therapy

Muscle growth & hyperplasia

Directly stimulates new muscle cell creation and growth — one of the few peptides that promotes muscle hyperplasia, not just hypertrophy.

Body recomposition

Simultaneous muscle gain and fat loss — particularly effective during caloric restriction phases.

Accelerated recovery

Enhanced tissue repair and reduced recovery time between training sessions.

Injury healing

Promotes repair of muscle, connective tissue, and bone through direct IGF-1 receptor stimulation.

Neuroprotection

IGF-1 receptors in the brain mediate neuroprotective effects — potentially beneficial for cognitive function.

Anti-aging

IGF-1 levels decline with age; restoration produces comprehensive anti-aging effects across multiple tissue types.

The Process

What to expect & when

Realistic timeline for IGF-LR3 results

1

Weeks 1–2

Recovery Improvement

Faster recovery between training sessions as IGF-1 receptor activation accelerates tissue repair.

2

Weeks 2–4

Body Composition Shift

Visible changes in muscle fullness and early fat reduction as anabolic and lipolytic pathways activate.

3

Weeks 4–8

Structural Changes

Measurable increases in lean mass. Fat reduction continues. Strength gains accelerate.

4

2–4 Months

Peak Results

Maximum body recomposition achieved. Long-term courses may produce permanent muscle fiber hyperplasia.

Common questions

Everything you need to know about IGF-LR3 therapy

Transparent Pricing

Consultation Fees

Physician-guided care with complete pricing clarity.

Generic Consultation

Includes Any & All Services

First Visit

$400

Follow-Up

$150

  • Complete health assessment
  • All service areas covered
  • Personalized treatment plan
  • Prescription if appropriate
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Specialized Consultation

Skin, Hair, Wellness, Labs, Galleri

First Visit

$300

Follow-Up

$150

  • Focused specialty review
  • Lab analysis included
  • Targeted treatment approach
  • Follow-up protocol
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Peptide Consultation

Weight loss & metabolic therapies

First Visit

$50

Follow-Up

$30

  • Metabolic assessment
  • GLP-1 or peptide evaluation
  • Dosing strategy
  • Prescription included
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IGF-LR3 — Anabolic Growth Factor | Get Simple Health | Simple Health